Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folK7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (193 aa)    
Predicted Functional Partners:
folP-2
Dihydropteroate synthase and related enzymes.
 
 
 0.998
folB
Dihydroneopterin aldolase.
  
 
 0.994
folE
GTP cyclohydrolase I.
 
  
 0.886
folE-2
GTP cyclohydrolase I.
 
  
 0.882
chlD
Protoporphyrin IX Mg-chelatase subunit ChlD; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
  
    0.718
ribD-2
Pyrimidine reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.704
Pro_0317
NUDIX/MutT family pyrophosphohydrolase.
     
 0.673
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.656
folC
Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
  
 0.641
nnrE
Predicted sugar kinase fused to uncharacterized domain; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydrata [...]
     
 0.624
Your Current Organism:
Prochlorococcus marinus CCMP1375
NCBI taxonomy Id: 167539
Other names: P. marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus SS120, Prochlorococcus marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus subsp. marinus str. SS120
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