Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptaBioD-like N-terminal domain of phosphotransacetylase. (356 aa)    
Predicted Functional Partners:
Pro_0478
Cyanobacteria-specific protein; Containing SMF/DprA family nucleotide binding domain fused to metal-binding center.
       0.686
fabG-2
Short-chain dehydrogenase/reductase family enzyme.
     
 0.608
Pro_0479
Uncharacterized conserved protein; Belongs to the UPF0234 family.
       0.527
Pro_0480
Predicted protein.
       0.459
ndhO
Uncharacterized protein; NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
  
     0.458
Pro_0575
AbrB family transciptional regulator; Contains a conserved domain in cyanobacteria. Same domain in Pro0615, Pro0616, Pro1459.
  
     0.455
acs
Acyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
   
 0.454
Pro_1459
AbrB family transciptional regulator; Contains a conserved domain in cyanobacteria. Same domain in Pro0575, Pro0615, Pro01459.
  
     0.451
Pro_0390
Uncharacterized protein; Conserved in cyanobacteria.
  
     0.449
Pro_0300
Uncharacterized protein; Conserved in cyanobacteria.
  
     0.421
Your Current Organism:
Prochlorococcus marinus CCMP1375
NCBI taxonomy Id: 167539
Other names: P. marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus SS120, Prochlorococcus marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus subsp. marinus str. SS120
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