Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hflCMembrane protease subunits; Stomatin/prohibitin homolog. (269 aa)    
Predicted Functional Partners:
cyoA
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
   0.672
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.658
ftsH-3
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
   
 0.658
ftsH-4
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.658
ftsH-2
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.657
glpG
Membrane serine protease of rhomboid family.
   
 0.650
pqqL-2
Zn-dependent peptidase; Belongs to the peptidase M16 family.
  
 0.646
Pro_0480
Predicted protein.
       0.633
pqqL
Zn-dependent peptidase.
   
 0.576
Pro_0498
Uncharacterized membrane protein; Conserved in cyanobacteria, contains TPR repeats.
  
     0.548
Your Current Organism:
Prochlorococcus marinus CCMP1375
NCBI taxonomy Id: 167539
Other names: P. marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus SS120, Prochlorococcus marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus subsp. marinus str. SS120
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