Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rlmHUncharacterized conserved protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (145 aa)    
Predicted Functional Partners:
rsfS
Uncharacterized similar to plant Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.804
Pro_0762
Predicted protein.
       0.728
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.710
umuD
UmuD ortholog, peptidase family S24; Distinct subfamily; Belongs to the peptidase S24 family.
       0.657
dinP
Nucleotidyltransferase/DNA polymerase; Involved in DNA repair (SOS pathway).
       0.651
polA
DNA polymerase I 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.596
Pro_0758
Predicted protein.
       0.548
rsmI
Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
   
 0.544
sun
tRNA and rRNA cytosine-C5-methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.543
Pro_1141
N6-adenine-specific methylase.
 
   
 0.541
Your Current Organism:
Prochlorococcus marinus CCMP1375
NCBI taxonomy Id: 167539
Other names: P. marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus SS120, Prochlorococcus marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus subsp. marinus str. SS120
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