node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysG | hemA | P9515_18851 | P9515_08151 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.611 |
cysG | hemB | P9515_18851 | P9515_02451 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.730 |
cysG | hemC | P9515_18851 | P9515_05591 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.979 |
cysG | hemD | P9515_18851 | P9515_01271 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | Putative uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.995 |
cysG | hemE | P9515_18851 | P9515_06481 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase (URO-D); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.932 |
cysG | hemL | P9515_18851 | P9515_05471 | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.501 |
glgC | glpX | P9515_08141 | P9515_08161 | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | 0.644 |
glgC | hemA | P9515_08141 | P9515_08151 | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.616 |
glgC | rpe | P9515_08141 | P9515_08171 | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | COG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]. | 0.553 |
glpX | glgC | P9515_08161 | P9515_08141 | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.644 |
glpX | hemA | P9515_08161 | P9515_08151 | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.796 |
glpX | rpe | P9515_08161 | P9515_08171 | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | COG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]. | 0.717 |
gltX | hemA | P9515_05371 | P9515_08151 | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.935 |
gltX | hemB | P9515_05371 | P9515_02451 | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.463 |
hemA | cysG | P9515_08151 | P9515_18851 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. | 0.611 |
hemA | glgC | P9515_08151 | P9515_08141 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.616 |
hemA | glpX | P9515_08151 | P9515_08161 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. | 0.796 |
hemA | gltX | P9515_08151 | P9515_05371 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.935 |
hemA | hemB | P9515_08151 | P9515_02451 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.864 |
hemA | hemC | P9515_08151 | P9515_05591 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.984 |