STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein Cse1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (334 aa)    
Predicted Functional Partners:
KNB53590.1
CRISPR-associated protein Cas2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
KNB53588.1
CRISPR-associated protein Cas3; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.985
KNB53586.1
CRISPR-associated protein Cse4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.983
KNB53587.1
CRISPR-associated protein Cas5; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.981
KNB53585.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.967
KNB53583.1
CRISPR-associated protein Cas3; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.956
KNB53584.1
CRISPR-associated protein Cse1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.953
KNB51112.1
DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.711
KNB49329.1
Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.711
KNB51770.1
Peptidase S9; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.454
Your Current Organism:
Streptomyces caatingaensis
NCBI taxonomy Id: 1678637
Other names: S. caatingaensis
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.