STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadE-2NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (584 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.980
KNB52653.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.959
ppnK
Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.957
KNB53214.1
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.954
KNB52062.1
Nicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
  
 
 0.948
KNB52063.1
Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 
 0.948
KNB51829.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.920
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
0.918
KNB51369.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.916
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.904
Your Current Organism:
Streptomyces caatingaensis
NCBI taxonomy Id: 1678637
Other names: S. caatingaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.