STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KNB52073.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)    
Predicted Functional Partners:
KNB52129.1
Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.757
KNB52074.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
KNB52075.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
KNB52130.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.688
KNB51314.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.598
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.598
KNB52077.1
Diguanylate cyclase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
    0.587
KNB52131.1
Integral membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.584
KNB52076.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.584
KNB52078.1
3-dehydroquinate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.584
Your Current Organism:
Streptomyces caatingaensis
NCBI taxonomy Id: 1678637
Other names: S. caatingaensis
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