node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALE53939.1 | ALE56029.1 | AC233_03740 | AC233_16130 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.445 |
ALE53939.1 | ALE56441.1 | AC233_03740 | AC233_03770 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
ALE53939.1 | ALE56845.1 | AC233_03740 | AC233_20400 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.781 |
ALE53939.1 | ALE56846.1 | AC233_03740 | AC233_20405 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6X reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.806 |
ALE53939.1 | ALE56847.1 | AC233_03740 | AC233_20410 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6A synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.711 |
ALE53939.1 | ALE56850.1 | AC233_03740 | AC233_20430 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.745 |
ALE53939.1 | ALE56851.1 | AC233_03740 | AC233_20435 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of precorrin-3 from precorrin-2; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.746 |
ALE53939.1 | ALE56852.1 | AC233_03740 | AC233_20440 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology; Start codon location was manually corrected by using GenomeMatcher. | 0.973 |
ALE53939.1 | ALE59347.1 | AC233_03740 | AC233_33255 | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
ALE55481.1 | ALE56029.1 | AC233_12975 | AC233_16130 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.599 |
ALE56029.1 | ALE53939.1 | AC233_16130 | AC233_03740 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.445 |
ALE56029.1 | ALE55481.1 | AC233_16130 | AC233_12975 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.599 |
ALE56029.1 | ALE56441.1 | AC233_16130 | AC233_03770 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.532 |
ALE56029.1 | ALE56845.1 | AC233_16130 | AC233_20400 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.778 |
ALE56029.1 | ALE56846.1 | AC233_16130 | AC233_20405 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6X reductase; CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.557 |
ALE56029.1 | ALE56847.1 | AC233_16130 | AC233_20410 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6A synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.643 |
ALE56029.1 | ALE56850.1 | AC233_16130 | AC233_20430 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Precorrin isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.778 |
ALE56029.1 | ALE56851.1 | AC233_16130 | AC233_20435 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of precorrin-3 from precorrin-2; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.695 |
ALE56029.1 | ALE56852.1 | AC233_16130 | AC233_20440 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology; Start codon location was manually corrected by using GenomeMatcher. | 0.916 |
ALE56029.1 | ALE59347.1 | AC233_16130 | AC233_33255 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.509 |