STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPS_0482Serine protease; Identified by similarity to SP:Q92743; match to protein family HMM PF00089. (423 aa)    
Predicted Functional Partners:
CPS_0481
FHA domain protein; Identified by similarity to OMNI:NTL01BL0696; match to protein family HMM PF00498.
 
     0.952
rseA
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
  
 
 0.701
CPS_4394
Serine protease; Identified by match to protein family HMM PF00089.
  
     0.584
CPS_2152
Thrombospondin type 3 repeat family protein/Calx-beta domain protein; Identified by match to protein family HMM PF03160.
  
    0.508
CPS_0310
TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719.
 
 0.463
CPS_0684
Putative TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.448
CPS_1206
Putative outer membrane porin; Identified by match to protein family HMM PF00267.
  
 
 
 0.448
CPS_3328
Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
  
 0.438
rplY
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
   0.418
CPS_3987
Identified by match to protein family HMM PF00149.
 
 
   0.407
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.