STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Identified by similarity to GP:13540428; match to protein family HMM PF01717. (347 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.987
metH
5-methyltetrahydrofolate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.984
metC
Cystathionine beta-lyase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01324.
  
 
 0.969
metB
Cystathionine gamma-synthase; Identified by similarity to SP:P00935; match to protein family HMM PF01053; match to protein family HMM TIGR02080.
  
 
 0.968
metL
Aspartokinase/homoserine dehydrogenase II; Identified by similarity to SP:P00562; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF03447; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.955
megL
Methionine gamma-lyase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01328.
  
 
 0.949
CPS_2546
O-acetylhomoserine/O-acetylserine sulfhydrylase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326.
  
 
 0.938
thrA
Aspartokinase/homoserine dehydrogenase, threonine-sensitive; Identified by similarity to SP:P27725; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.928
CPS_0276
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.918
metG
methionyl-tRNA synthetase, beta subunit; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.918
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.