STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPS_1986Identified by similarity to SP:P03807; match to protein family HMM PF00582. (316 aa)    
Predicted Functional Partners:
fnr
Fumarate/nitrate reduction regulatory protein; Identified by similarity to SP:P03019; match to protein family HMM PF00027; match to protein family HMM PF00325.
 
  
 0.817
CPS_2610
Putative membrane protein; Identified by similarity to OMNI:NTL01YP1193.
  
     0.700
CPS_2208
TPR domain protein; May be involved in cell division.
  
     0.683
CPS_3175
Conserved hypothetical protein; Identified by similarity to SP:Q9KT06.
  
     0.662
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.661
seqA
seqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.645
CPS_2612
37-kD nucleoid-associated bacterial protein; Identified by similarity to SP:P33920; match to protein family HMM PF04245.
  
     0.600
lptC
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
 
     0.594
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
 
  
 0.572
CPS_2611
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SF2126; match to protein family HMM PF07208; Belongs to the UPF0352 family.
  
     0.567
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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