Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lysCAspartokinase III, lysine-sensitive; Identified by similarity to SP:P08660; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. (456 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.993
metL
Aspartokinase/homoserine dehydrogenase II; Identified by similarity to SP:P00562; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF03447; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
0.968
thrA
Aspartokinase/homoserine dehydrogenase, threonine-sensitive; Identified by similarity to SP:P27725; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
0.967
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.941
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 
 0.937
CPS_4492
Putative pyridoxal-dependent decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM PF02784; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.934
thrC
Threonine synthase; Identified by similarity to SP:P00934; match to protein family HMM PF00291; match to protein family HMM TIGR00260.
 
 
 0.910
argG
Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.898
metA
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
  
 0.889
dapD
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR00965; Belongs to the transferase hexapeptide repeat family.
 
  
 0.857
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.