STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trx2Thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068. (144 aa)    
Predicted Functional Partners:
CPS_1798
ATP-dependent peptidase, M41 family; Identified by similarity to GP:8051696; match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF07724; Belongs to the AAA ATPase family.
 
 
 0.537
CPS_2237
Microbial collagenase; Identified by similarity to SP:P43154; match to protein family HMM PF01752.
  
    0.533
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
 
 
 0.526
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
 
  
 0.490
groEL
Chaperone protein GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.485
CPS_1795
ATP-dependent peptidase, M41 family; Identified by similarity to GP:8051696; match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF07724; Belongs to the AAA ATPase family.
  
 
 0.478
CPS_3358
Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.442
CPS_1923
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
  
 
 0.433
fadH1
2,4-dienoyl-CoA reductase; Identified by similarity to SP:P42593; match to protein family HMM PF00070; match to protein family HMM PF00724; match to protein family HMM PF07992.
  
 
 0.405
gor
Glutathione reductase; Identified by similarity to SP:P06715; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01421.
  
 
 0.402
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.