STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holBDNA polymerase III, delta prime subunit; Identified by similarity to SP:P28631. (331 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.982
dnaE
DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.
 
 0.982
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
  
 0.980
holA
DNA polymerase III, delta subunit; Identified by similarity to SP:P28630; match to protein family HMM PF06144; match to protein family HMM TIGR01128.
   
 0.979
holC
DNA polymerase III, chi subunit; Identified by similarity to SP:P28905; match to protein family HMM PF04364.
    
 0.978
CPS_4955
Exonuclase; Identified by match to protein family HMM PF00929.
   
 0.943
CPS_0780
Exonuclease; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573.
 
 0.930
dnaX
DNA polymerase III, gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
  
 
0.927
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
  
 0.819
CPS_2304
Putative type IV pilus biogenesis protein pilZ; Identified by similarity to OMNI:NTL03PA02960; match to protein family HMM PF07238.
       0.760
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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