CPS_2655 protein (Colwellia psychrerythraea)

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second shell of interactors

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a 3D structure is known or predicted

Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

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Score

CPS_2655

Conserved hypothetical protein; This gene assignment is based partly on a multiple alignment of the best pairwise matches. (300 aa)

Predicted Functional Partners:

CPS_4859

0.756

CPS_1277

0.746

CPS_3588

0.743

CPS_2793

0.740

CPS_3879

0.711

CPS_2474

0.685

CPS_2470

0.676

CPS_3840

0.651

CPS_4495

0.634

CPS_4294

0.608

Your Current Organism:

Colwellia psychrerythraea

NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
CPS_1277	CPS_2470	Hypothetical protein; Identified by Glimmer2; putative.	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	0.716
CPS_1277	CPS_2474	Hypothetical protein; Identified by Glimmer2; putative.	Bacterial extracellular solute-binding protein, family 3.	0.674
CPS_1277	CPS_2655	Hypothetical protein; Identified by Glimmer2; putative.	Conserved hypothetical protein; This gene assignment is based partly on a multiple alignment of the best pairwise matches.	0.746
CPS_1277	CPS_2793	Hypothetical protein; Identified by Glimmer2; putative.	Putative amino acid-binding protein.	0.750
CPS_1277	CPS_3588	Hypothetical protein; Identified by Glimmer2; putative.	Conserved hypothetical protein.	0.762
CPS_1277	CPS_3840	Hypothetical protein; Identified by Glimmer2; putative.	Putative lipoprotein.	0.769
CPS_1277	CPS_4495	Hypothetical protein; Identified by Glimmer2; putative.	Sensory box sensor histidine kinase; Identified by similarity to GP:27358467; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.	0.611
CPS_1277	CPS_4859	Hypothetical protein; Identified by Glimmer2; putative.	Putative cation efflux protein.	0.753
CPS_2470	CPS_1277	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	Hypothetical protein; Identified by Glimmer2; putative.	0.716
CPS_2470	CPS_2474	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	Bacterial extracellular solute-binding protein, family 3.	0.453
CPS_2470	CPS_2655	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	Conserved hypothetical protein; This gene assignment is based partly on a multiple alignment of the best pairwise matches.	0.676
CPS_2470	CPS_2793	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	Putative amino acid-binding protein.	0.649
CPS_2470	CPS_3588	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	Conserved hypothetical protein.	0.691
CPS_2470	CPS_3840	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	Putative lipoprotein.	0.674
CPS_2474	CPS_1277	Bacterial extracellular solute-binding protein, family 3.	Hypothetical protein; Identified by Glimmer2; putative.	0.674
CPS_2474	CPS_2470	Bacterial extracellular solute-binding protein, family 3.	Bacterial extracellular solute-binding protein, family 3; Identified by match to protein family HMM PF00497.	0.453
CPS_2474	CPS_2655	Bacterial extracellular solute-binding protein, family 3.	Conserved hypothetical protein; This gene assignment is based partly on a multiple alignment of the best pairwise matches.	0.685
CPS_2474	CPS_2793	Bacterial extracellular solute-binding protein, family 3.	Putative amino acid-binding protein.	0.749
CPS_2474	CPS_3588	Bacterial extracellular solute-binding protein, family 3.	Conserved hypothetical protein.	0.669
CPS_2474	CPS_3840	Bacterial extracellular solute-binding protein, family 3.	Putative lipoprotein.	0.721

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.949

expected number of edges:

10

PPI enrichment p-value:

6.12e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0098930

Axonal transport

5 of 32

2.37

3.67

5.68e-08

GO:0047497

Mitochondrion transport along microtubule

4 of 12

2.7

3.6

1.89e-07

GO:0006607

NLS-bearing protein import into nucleus

4 of 16

2.58

3.41

3.47e-07

GO:0010970

Transport along microtubule

6 of 110

1.92

3.05

1.03e-07

GO:0000413

Protein peptidyl-prolyl isomerization

4 of 29

2.32

2.87

2.53e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0061665

SUMO ligase activity

4 of 13

2.67

3.31

6.55e-07

GO:0008574

Plus-end-directed microtubule motor activity

2 of 11

2.44

1.02

0.0137

GO:0031267

Small GTPase binding

4 of 230

1.42

0.89

0.0104

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044614

Nuclear pore cytoplasmic filaments

4 of 6

3.0

4.11

2.87e-08

GO:0005642

Annulate lamellae

4 of 7

2.94

4.09

2.87e-08

GO:0106068

SUMO ligase complex

4 of 11

2.74

3.97

3.74e-08

GO:0042405

Nuclear inclusion body

4 of 11

2.74

3.97

3.74e-08

GO:0044615

Nuclear pore nuclear basket

4 of 13

2.67

3.89

4.65e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15666

Establishment of mitochondrion localization, and CH-like domain in sperm protein

3 of 11

2.61

1.92

0.00029

CL:5958

Transport of Mature mRNA Derived from an Intronless Transcript

3 of 29

2.19

1.58

0.00098

CL:16207

RHO GTPases activate KTN1

2 of 5

2.78

1.33

0.0039

CL:15669

MIRO domain, and HAP1, N-terminal

2 of 5

2.78

1.33

0.0039

CL:5999

Mixed, incl. Nuclear pore central transport channel, and Nuclear pore cytoplasmic filaments

2 of 7

2.64

1.25

0.0052

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-3301854

Nuclear Pore Complex (NPC) Disassembly

4 of 41

2.17

2.56

7.94e-06

MAP-159231

Transport of Mature mRNA Derived from an Intronless Transcript

4 of 40

2.18

2.56

7.94e-06

MAP-159227

Transport of the SLBP independent Mature mRNA

4 of 41

2.17

2.56

7.94e-06

MAP-159234

Transport of Mature mRNAs Derived from Intronless Transcripts

4 of 44

2.14

2.54

7.94e-06

MAP-159230

Transport of the SLBP Dependant Mature mRNA

4 of 43

2.15

2.54

7.94e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044614

Nuclear pore cytoplasmic filaments

4 of 5

3.08

4.21

2.01e-08

GOCC:0031967

Organelle envelope

6 of 427

1.33

1.42

6.42e-05

GOCC:0043229

Intracellular organelle

11 of 6905

0.38

0.29

0.0165

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00160

Ran-binding domain

2 of 8

2.58

1.04

0.0130

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