STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrRSigma-54 dependent transcriptional regulator TyrR; Identified by similarity to SP:P07604; match to protein family HMM PF00158; match to protein family HMM PF01842; match to protein family HMM TIGR01199. (516 aa)    
Predicted Functional Partners:
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.770
pheA
Chorismate mutase/prephenate dehydratase; Identified by similarity to SP:Q02286; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM TIGR01797.
      
 0.623
tyrA
Chorismate mutase/prephenate dehydrogenase; Identified by similarity to SP:P07023; match to protein family HMM PF01817; match to protein family HMM PF02153; match to protein family HMM TIGR01799.
      
 0.620
phhB
Pterin-4-alpha-carbinolamine dehydratase; Identified by match to protein family HMM PF01329.
     
 0.537
metJ
Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
  
   
 0.521
argR
Arginine repressor; Regulates arginine biosynthesis genes.
      
 0.487
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
      
 0.486
nrdR
Conserved hypothetical protein TIGR00244; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.485
argR-2
Putative arginine repressor; Regulates arginine biosynthesis genes.
      
 0.484
CPS_3763
Identified by match to protein family HMM PF01557.
     
 0.481
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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