STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPS_3959RNA polymerase sigma factor, sigma-70 family; Identified by similarity to SP:Q06198; match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)    
Predicted Functional Partners:
CPS_3958
Putative regulatory protein; Identified by similarity to SP:P23485; match to protein family HMM PF04773.
 
 
 0.871
CPS_0794
RNA polymerase sigma factor, sigma-70 family; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.762
CPS_4364
RNA polymerase sigma-70 factor, ECF subfamily; Identified by similarity to SP:Q06198; match to protein family HMM PF04542; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.759
CPS_4850
RNA polymerase sigma factor, sigma-70 family; Identified by similarity to SP:Q06198; match to protein family HMM PF04542; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.753
CPS_3852
RNA polymerase sigma factor, sigma-70 family; Identified by similarity to SP:O05404; match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.739
rseA
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
  
 
 0.700
CPS_0962
RNA polymerase sigma-70 factor, ECF subfamily; Identified by similarity to SP:Q45585; match to protein family HMM PF04542; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.688
CPS_3165
RNA polymerase sigma-70 factor, ECF subfamily; Identified by match to protein family HMM PF04542; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.590
CPS_2817
Putative regulatory protein; Identified by match to protein family HMM PF04773.
 
 
 0.562
CPS_0244
Putative regulatory protein; Identified by similarity to SP:P23485; match to protein family HMM PF04773.
 
 
 0.533
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.