STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rseBsigma-E factor regulatory protein RseB; Identified by similarity to SP:P46186; match to protein family HMM PF03888. (337 aa)    
Predicted Functional Partners:
rseA
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
 
 
 0.992
rseC
sigma-E factor regulatory protein RseC; Identified by similarity to SP:P46187; match to protein family HMM PF04246.
 
  
 0.985
rpoE
RNA polymerase sigma-24 factor; Identified by similarity to SP:P34086; match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family. ECF subfamily.
 
 0.911
cysB
Cys regulon transcription activator; Identified by similarity to SP:P06613; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.692
CPS_2000
Conserved hypothetical protein; Identified by similarity to OMNI:VC2235.
  
     0.681
CPS_3665
Identified by match to protein family HMM PF02325.
  
     0.576
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.561
CPS_4432
Conserved hypothetical protein; Identified by similarity to OMNI:VC0581.
  
     0.540
CPS_4533
Identified by match to protein family HMM PF05494.
  
     0.540
recO
Recombination protein O; Involved in DNA repair and RecF pathway recombination.
 
    0.498
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.