node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPS_4132 | CPS_4149 | CPS_4132 | CPS_4149 | Putative aminomethyltransferase; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.534 |
CPS_4132 | hemD | CPS_4132 | CPS_0073 | Putative aminomethyltransferase; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.510 |
CPS_4149 | CPS_4132 | CPS_4149 | CPS_4132 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Putative aminomethyltransferase; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.534 |
CPS_4149 | apaH | CPS_4149 | CPS_4527 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.674 |
CPS_4149 | bamE | CPS_4149 | CPS_3826 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | SmpA/OmlA family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.692 |
CPS_4149 | ftsB | CPS_4149 | CPS_1071 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.719 |
CPS_4149 | ftsQ | CPS_4149 | CPS_4462 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.678 |
CPS_4149 | hemD | CPS_4149 | CPS_0073 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.575 |
CPS_4149 | mutY | CPS_4149 | CPS_4148 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.857 |
CPS_4149 | rpmF | CPS_4149 | CPS_2294 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Ribosomal protein L32; Identified by similarity to SP:P02435; match to protein family HMM PF01783; match to protein family HMM TIGR01031; Belongs to the bacterial ribosomal protein bL32 family. | 0.567 |
CPS_4149 | secE | CPS_4149 | CPS_4778 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.612 |
CPS_4149 | sspB | CPS_4149 | CPS_4436 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Identified by similarity to SP:P25663; match to protein family HMM PF04386. | 0.709 |
apaH | CPS_4149 | CPS_4527 | CPS_4149 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.674 |
apaH | bamE | CPS_4527 | CPS_3826 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | SmpA/OmlA family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.625 |
apaH | ftsB | CPS_4527 | CPS_1071 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.662 |
apaH | ftsQ | CPS_4527 | CPS_4462 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.651 |
apaH | rpmF | CPS_4527 | CPS_2294 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Ribosomal protein L32; Identified by similarity to SP:P02435; match to protein family HMM PF01783; match to protein family HMM TIGR01031; Belongs to the bacterial ribosomal protein bL32 family. | 0.587 |
apaH | secE | CPS_4527 | CPS_4778 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.683 |
apaH | sspB | CPS_4527 | CPS_4436 | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Identified by similarity to SP:P25663; match to protein family HMM PF04386. | 0.688 |
bamE | CPS_4149 | CPS_3826 | CPS_4149 | SmpA/OmlA family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.692 |