node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPS_4237 | CPS_4239 | CPS_4237 | CPS_4239 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA03855. | 0.783 |
CPS_4237 | mutL | CPS_4237 | CPS_0323 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.738 |
CPS_4237 | polA | CPS_4237 | CPS_4978 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.825 |
CPS_4237 | recA | CPS_4237 | CPS_4134 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.798 |
CPS_4237 | recJ | CPS_4237 | CPS_4094 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.815 |
CPS_4237 | sbcD | CPS_4237 | CPS_2849 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.802 |
CPS_4237 | selO | CPS_4237 | CPS_4238 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | Conserved hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). | 0.776 |
CPS_4237 | topA | CPS_4237 | CPS_1197 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.889 |
CPS_4237 | topB | CPS_4237 | CPS_4792 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | DNA topoisomerase III; Identified by similarity to SP:P14294; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01056. | 0.908 |
CPS_4237 | xni | CPS_4237 | CPS_3538 | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.708 |
CPS_4239 | CPS_4237 | CPS_4239 | CPS_4237 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA03855. | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | 0.783 |
CPS_4239 | selO | CPS_4239 | CPS_4238 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA03855. | Conserved hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). | 0.773 |
mutL | CPS_4237 | CPS_0323 | CPS_4237 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | 0.738 |
mutL | polA | CPS_0323 | CPS_4978 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.919 |
mutL | recA | CPS_0323 | CPS_4134 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.596 |
mutL | recJ | CPS_0323 | CPS_4094 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | single-stranded-DNA-specific exonuclease RecJ; Identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.543 |
mutL | topA | CPS_0323 | CPS_1197 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.472 |
mutL | xni | CPS_0323 | CPS_3538 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.864 |
polA | CPS_4237 | CPS_4978 | CPS_4237 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | 0.825 |
polA | mutL | CPS_4978 | CPS_0323 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.919 |