STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
putABifunctional putA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1275 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.950
lhpI
Putative ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Together with LhpH, is involved in a metabolic pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline. To a much lesser extent, can also reduce Delta(1)-piperideine-2-carboxylate (Pip2C) to L-pipecolate in vitro; however, this activity has likely no physiological significance in vivo since C.psychrerythraea probably possesses no ability to metabolize D-lysine via the L-pipecolate pathway. Does not [...]
  
 
 0.940
CPS_2747
Putative ornithine cyclodeaminase; Identified by match to protein family HMM PF02423.
  
 
 0.940
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.940
CPS_0068
Sensory box sensor histidine kinase/response regulator; Identified by similarity to OMNI:NTL03PA03271; match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
  
  
 0.938
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.938
glnA
Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.
   
 
 0.935
CPS_4677
Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
   
 
 0.935
CPS_2802
Identified by match to protein family HMM PF05088.
  
  
 0.932
CPS_2694
Identified by match to protein family HMM PF05088.
  
  
 0.929
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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