STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topBDNA topoisomerase III; Identified by similarity to SP:P14294; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01056. (649 aa)    
Predicted Functional Partners:
CPS_0024
Topoisomerase DNA-binding C4 zinc finger domain protein; Identified by similarity to SP:P39814; match to protein family HMM PF01396.
  
 
 0.847
recQ
ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.
 
 0.847
CPS_4237
RecQ domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614.
 0.827
sbcC
Exonuclease SbcC; Identified by match to protein family HMM TIGR00618.
 
 0.715
CPS_0751
Cold-active alkaline serine protease; Identified by similarity to GP:2921857; match to protein family HMM PF00082; match to protein family HMM PF02225; match to protein family HMM PF04151.
      
 0.675
CPS_2871
Cold-active alkaline serine protease; Identified by similarity to GP:2921857; match to protein family HMM PF00082; match to protein family HMM PF02225; match to protein family HMM PF04151; Belongs to the peptidase S8 family.
      
 0.675
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.643
CPS_2945
Putative DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
  
 0.610
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.604
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
  
 0.579
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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