STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.998
ilvD
Dihydroxy-acid dehydratase; Identified by similarity to SP:P05791; match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family.
  
 0.981
CPS_2080
Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family.
  
 0.968
thrA
Aspartokinase/homoserine dehydrogenase, threonine-sensitive; Identified by similarity to SP:P27725; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 
 0.933
CPS_2904
Glu/Leu/Phe/Val dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.926
metL
Aspartokinase/homoserine dehydrogenase II; Identified by similarity to SP:P00562; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF03447; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.922
CPS_3232
Aminotransferase, class I; Identified by match to protein family HMM PF00155.
  
 
 0.922
CPS_1583
2-oxoisovalerate dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:P09061; match to protein family HMM PF02779; match to protein family HMM PF02780.
  
 0.921
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.918
metB
Cystathionine gamma-synthase; Identified by similarity to SP:P00935; match to protein family HMM PF01053; match to protein family HMM TIGR02080.
   
 0.915
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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