STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaDGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (449 aa)    
Predicted Functional Partners:
CPS_4865
Xanthine dehydrogenase, molybdopterin binding subunit; Identified by similarity to GP:18655921; match to protein family HMM PF01315; match to protein family HMM PF02738.
 
 
 0.982
CPS_4864
Xanthine dehydrogenase, iron-sulfur binding subunit; Identified by similarity to GP:2956674; match to protein family HMM PF00111; match to protein family HMM PF00941; match to protein family HMM PF01799; match to protein family HMM PF03450.
 
  
  0.979
hpt
Hypoxanthine phosphoribosyltransferase; Identified by similarity to SP:P36766; match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.927
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
 0.915
deoD
Purine nucleoside phosphorylase; Identified by similarity to SP:P09743; match to protein family HMM PF01048; match to protein family HMM TIGR00107.
     
 0.900
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
CPS_4870
Conserved hypothetical protein; Identified by similarity to SP:P76341; match to protein family HMM PF00576; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
   
 0.852
CPS_4873
Putative membrane protein.
 
     0.849
CPS_4866
Putative xanthine dehydrogenase accessory protein XdhC; Identified by similarity to GP:4741723; match to protein family HMM PF02625.
 
    0.826
allA
Ureidoglycolate hydrolase; Identified by match to protein family HMM PF04115.
 
     0.780
Your Current Organism:
Colwellia psychrerythraea
NCBI taxonomy Id: 167879
Other names: C. psychrerythraea 34H, Colwellia psychrerythraea 34H, Colwellia psychrerythraea str. 34H, Colwellia psychrerythraea strain 34H, Colwellia sp. 34H
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