STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATC1_12191acyl-CoA hydrolase. (446 aa)    
Predicted Functional Partners:
GAP41693.1
Acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.908
ATC1_12168
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
    
 0.900
ATC1_12188
Pyruvate:ferredoxin oxidoreductase.
    
 0.883
ATC1_12187
Pyruvate:ferredoxin oxidoreductase.
    
 0.828
ATC1_12186
2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate.
    
  0.798
ATC1_12189
Protein containing 4Fe-4S dicluster domain.
  
 
  0.791
ATC1_12190
Hypothetical protein.
       0.773
ATC1_13763
Citrate synthase; Belongs to the citrate synthase family.
  
 0.768
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.739
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.705
Your Current Organism:
Flexilinea flocculi
NCBI taxonomy Id: 1678840
Other names: Anaerolineae bacterium TC1, CGMCC 1.5202, F. flocculi, Flexilinea flocculi Sun et al. 2016, JCM 30897, strain TC1
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