GAP42923.1 protein (Lentimicrobium saccharophilum)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

GAP42923.1

Thiosulfate reductase cytochrome b subunit. (228 aa)

Predicted Functional Partners:

GAP42922.1

0.966

GAP42283.1

0.778

GAP44675.1

0.778

GAP42924.1

0.610

GAP42921.1

0.561

GAP42282.1

0.524

GAP44676.1

0.511

GAP42210.1

0.455

GAP44679.1

0.448

GAP42920.1

0.442

Your Current Organism:

Lentimicrobium saccharophilum

NCBI taxonomy Id: 1678841
Other names: Bacteroidales bacterium TBC1, DSM 100618, JCM 30898, L. saccharophilum, Lentimicrobium saccharophilum Sun et al. 2016, strain TBC1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAP42210.1	GAP42282.1	TBC1_11339	TBC1_11411	Sulfide-quinone oxidoreductase.	Thiosulfate reductase cytochrome b subunit.	0.426
GAP42210.1	GAP42922.1	TBC1_11339	TBC1_111063	Sulfide-quinone oxidoreductase.	Cytochrome c554.	0.450
GAP42210.1	GAP42923.1	TBC1_11339	TBC1_111064	Sulfide-quinone oxidoreductase.	Thiosulfate reductase cytochrome b subunit.	0.455
GAP42282.1	GAP42210.1	TBC1_11411	TBC1_11339	Thiosulfate reductase cytochrome b subunit.	Sulfide-quinone oxidoreductase.	0.426
GAP42282.1	GAP42283.1	TBC1_11411	TBC1_11412	Thiosulfate reductase cytochrome b subunit.	Octaheme c-type cytochrome, tetrathionate reductase family.	0.937
GAP42282.1	GAP42922.1	TBC1_11411	TBC1_111063	Thiosulfate reductase cytochrome b subunit.	Cytochrome c554.	0.734
GAP42282.1	GAP42923.1	TBC1_11411	TBC1_111064	Thiosulfate reductase cytochrome b subunit.	Thiosulfate reductase cytochrome b subunit.	0.524
GAP42282.1	GAP44675.1	TBC1_11411	TBC1_12486	Thiosulfate reductase cytochrome b subunit.	Octaheme c-type cytochrome, tetrathionate reductase family.	0.784
GAP42282.1	GAP44679.1	TBC1_11411	TBC1_12490	Thiosulfate reductase cytochrome b subunit.	Rhodanese-related sulfurtransferase.	0.536
GAP42283.1	GAP42282.1	TBC1_11412	TBC1_11411	Octaheme c-type cytochrome, tetrathionate reductase family.	Thiosulfate reductase cytochrome b subunit.	0.937
GAP42283.1	GAP42922.1	TBC1_11412	TBC1_111063	Octaheme c-type cytochrome, tetrathionate reductase family.	Cytochrome c554.	0.590
GAP42283.1	GAP42923.1	TBC1_11412	TBC1_111064	Octaheme c-type cytochrome, tetrathionate reductase family.	Thiosulfate reductase cytochrome b subunit.	0.778
GAP42283.1	GAP44676.1	TBC1_11412	TBC1_12487	Octaheme c-type cytochrome, tetrathionate reductase family.	Thiosulfate reductase cytochrome b subunit.	0.784
GAP42283.1	GAP44679.1	TBC1_11412	TBC1_12490	Octaheme c-type cytochrome, tetrathionate reductase family.	Rhodanese-related sulfurtransferase.	0.535
GAP42920.1	GAP42921.1	TBC1_111061	TBC1_111062	Hypothetical protein.	Cytochrome C oxidase, cbb3-type, subunit III.	0.883
GAP42920.1	GAP42922.1	TBC1_111061	TBC1_111063	Hypothetical protein.	Cytochrome c554.	0.769
GAP42920.1	GAP42923.1	TBC1_111061	TBC1_111064	Hypothetical protein.	Thiosulfate reductase cytochrome b subunit.	0.442
GAP42920.1	GAP42924.1	TBC1_111061	TBC1_111065	Hypothetical protein.	Hypothetical protein.	0.540
GAP42921.1	GAP42920.1	TBC1_111062	TBC1_111061	Cytochrome C oxidase, cbb3-type, subunit III.	Hypothetical protein.	0.883
GAP42921.1	GAP42922.1	TBC1_111062	TBC1_111063	Cytochrome C oxidase, cbb3-type, subunit III.	Cytochrome c554.	0.662

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.659

expected number of edges:

11

PPI enrichment p-value:

4.68e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032259

Methylation

9 of 129

1.43

2.38

1.51e-09

GO:0009234

Menaquinone biosynthetic process

2 of 4

2.29

0.83

0.0299

GO:0008152

Metabolic process

11 of 1593

0.43

0.32

0.0100

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008168

Methyltransferase activity

9 of 92

1.58

3.06

4.10e-11

GO:0016740

Transferase activity

10 of 431

0.95

1.09

2.00e-07

GO:0003824

Catalytic activity

11 of 1535

0.44

0.36

0.0016

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043231

Intracellular membrane-bounded organelle

4 of 164

0.98

0.57

0.0276

GO:0016020

Membrane

7 of 595

0.66

0.42

0.0221

GO:0016021

Integral component of membrane

6 of 481

0.69

0.42

0.0276

GO:0110165

Cellular anatomical entity

11 of 1922

0.35

0.27

0.0221

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3564

Ubiquinone and other terpenoid-quinone biosynthesis, and Methyltransferase domain

8 of 37

1.92

4.3

9.55e-12

CL:3569

Ubiquinone and other terpenoid-quinone biosynthesis, and O-methyltransferase domain

6 of 18

2.11

4.11

9.13e-10

CL:3566

Mixed, incl. Methyltransferase domain 25, and NADPH-dependent FMN reductase-like

7 of 30

1.96

4.07

1.22e-10

CL:3589

Menaquinone metabolic process, and Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)

4 of 5

2.49

3.42

2.82e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00130

Ubiquinone and other terpenoid-quinone biosynthesis

9 of 46

1.88

4.77

2.83e-14

map01110

Biosynthesis of secondary metabolites

9 of 436

0.9

0.94

3.26e-06

map01100

Metabolic pathways

9 of 1101

0.5

0.38

0.0061

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0110165

Cellular anatomical entity

11 of 1364

0.5

0.41

0.00089

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13489

Methyltransferase domain

3 of 10

2.07

1.43

0.0017

PF05401

Nodulation protein S (NodS)

2 of 6

2.11

0.75

0.0398

PF01209

ubiE/COQ5 methyltransferase family

2 of 8

1.99

0.73

0.0425

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029063

S-adenosyl-L-methionine-dependent methyltransferase superfamily

9 of 97

1.56

2.89

1.52e-10

IPR013216

Methyltransferase type 11

4 of 25

1.79

1.65

0.00031

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