STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAP44901.1Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (337 aa)    
Predicted Functional Partners:
GAP43168.1
NAD(P)H-flavin reductase.
  
 0.990
pyrK
NAD(P)H-flavin reductase; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 0.939
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.848
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.836
TBC1_1142
glycine/D-amino acid oxidase.
  
 0.825
GAP43316.1
D-hydantoinase.
 
 0.799
GAP44830.1
Orotidine-5'-phosphate decarboxylase.
  
 
 0.795
GAP42221.1
Dihydroorotase.
  
 0.783
GAP44900.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
 
 
 
 0.771
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.770
Your Current Organism:
Lentimicrobium saccharophilum
NCBI taxonomy Id: 1678841
Other names: Bacteroidales bacterium TBC1, DSM 100618, JCM 30898, L. saccharophilum, Lentimicrobium saccharophilum Sun et al. 2016, strain TBC1
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