node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
InfB | KsgA | RY70_1669 | RY70_34 | Translation initiation factor IF-2. | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | 0.747 |
InfB | engD_1 | RY70_1669 | RY70_1266 | Translation initiation factor IF-2. | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.832 |
InfB | ffh_4 | RY70_1669 | RY70_409 | Translation initiation factor IF-2. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.706 |
InfB | ftsY | RY70_1669 | RY70_1848 | Translation initiation factor IF-2. | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.767 |
InfB | guaA_1 | RY70_1669 | RY70_883 | Translation initiation factor IF-2. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.589 |
InfB | pheT | RY70_1669 | RY70_1225 | Translation initiation factor IF-2. | Phenylalanine-tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.782 |
InfB | prfA | RY70_1669 | RY70_1535 | Translation initiation factor IF-2. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.515 |
InfB | secY | RY70_1669 | RY70_1685 | Translation initiation factor IF-2. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.871 |
KsgA | InfB | RY70_34 | RY70_1669 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | Translation initiation factor IF-2. | 0.747 |
KsgA | engD_1 | RY70_34 | RY70_1266 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.880 |
KsgA | ffh_4 | RY70_34 | RY70_409 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.757 |
KsgA | ftsY | RY70_34 | RY70_1848 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.798 |
KsgA | guaA_1 | RY70_34 | RY70_883 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.488 |
KsgA | pheT | RY70_34 | RY70_1225 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | Phenylalanine-tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.634 |
KsgA | secY | RY70_34 | RY70_1685 | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.733 |
engD_1 | InfB | RY70_1266 | RY70_1669 | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Translation initiation factor IF-2. | 0.832 |
engD_1 | KsgA | RY70_1266 | RY70_34 | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein. | 0.880 |
engD_1 | ffh_4 | RY70_1266 | RY70_409 | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.786 |
engD_1 | ftsY | RY70_1266 | RY70_1848 | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.808 |
engD_1 | guaA_1 | RY70_1266 | RY70_883 | Translation-associated GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.640 |