node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gltB | ilvB | RY70_964 | RY70_421 | Ferredoxin-dependent glutamate synthase. | Acetolactate synthase large subunit. | 0.692 |
gltB | ilvC2 | RY70_964 | RY70_211 | Ferredoxin-dependent glutamate synthase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.705 |
gltB | ilvC_2 | RY70_964 | RY70_214 | Ferredoxin-dependent glutamate synthase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.705 |
gltB | ilvD | RY70_964 | RY70_716 | Ferredoxin-dependent glutamate synthase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.903 |
gltB | ilvN | RY70_964 | RY70_422 | Ferredoxin-dependent glutamate synthase. | Acetolactate synthase small subunit. | 0.812 |
gltB | leuA | RY70_964 | RY70_1901 | Ferredoxin-dependent glutamate synthase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.468 |
gltB | leuB | RY70_964 | RY70_470 | Ferredoxin-dependent glutamate synthase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.733 |
gltB | leuC | RY70_964 | RY70_273 | Ferredoxin-dependent glutamate synthase. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.775 |
gltB | leuD | RY70_964 | RY70_274 | Ferredoxin-dependent glutamate synthase. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.729 |
gltB | tdcB | RY70_964 | RY70_11 | Ferredoxin-dependent glutamate synthase. | Threonine dehydratase. | 0.798 |
ilvB | gltB | RY70_421 | RY70_964 | Acetolactate synthase large subunit. | Ferredoxin-dependent glutamate synthase. | 0.692 |
ilvB | ilvC2 | RY70_421 | RY70_211 | Acetolactate synthase large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.990 |
ilvB | ilvC_2 | RY70_421 | RY70_214 | Acetolactate synthase large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.991 |
ilvB | ilvD | RY70_421 | RY70_716 | Acetolactate synthase large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.972 |
ilvB | ilvN | RY70_421 | RY70_422 | Acetolactate synthase large subunit. | Acetolactate synthase small subunit. | 0.999 |
ilvB | leuA | RY70_421 | RY70_1901 | Acetolactate synthase large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.954 |
ilvB | leuB | RY70_421 | RY70_470 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.983 |
ilvB | leuC | RY70_421 | RY70_273 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.610 |
ilvB | leuD | RY70_421 | RY70_274 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.621 |
ilvB | tdcB | RY70_421 | RY70_11 | Acetolactate synthase large subunit. | Threonine dehydratase. | 0.964 |