metK protein (Bifidobacterium bifidum) - STRING interaction network

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metK

S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (405 aa)

Predicted Functional Partners:

metE

0.977

metY

0.907

cth

0.907

RY70_1555

0.907

HgiDIM

0.905

purF

0.719

pth

0.703

MscL

0.673

adh2

0.654

PriA

0.651

Your Current Organism:

Bifidobacterium bifidum

NCBI taxonomy Id: 1681
Other names: AS 1.2212, ATCC 29521, Actinobacterium bifidum, Actinomyces bifidus, Actinomyces parabifidus, B. bifidum, BCRC 14615, Bacillus bifidus, Bacillus bifidus communis, Bacterium bifidum, Bacteroides bifidus, Bifidibacterium bifidum, CCRC 14615, CCRC:14615, CCUG 18364, CCUG 45217, CIP 56.7, Cohnistreptothrix bifidus, DSM 20456, IFO 14252, KCTC 3202, LMG 11041, LMG 8810, LMG:11041, LMG:8810, Lactobacillus bifidus type II, Lactobacillus parabifidus, NBRC 100015, NBRC 14252, NCFB 2715, NCIMB 702715, NCTC 13001, Nocardia bifida, Tissieria bifida, strain Ti

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HgiDIM	metK	RY70_180	RY70_718	Cytosine-specific methyltransferase.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.905
MscL	metK	RY70_70	RY70_718	Large-conductance mechanosensitive channel protein.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.673
PriA	metK	RY70_719	RY70_718	Primosomal protein N'.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.651
PriA	pth	RY70_719	RY70_815	Primosomal protein N'.	Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.	0.483
RY70_1555	cth	RY70_1555	RY70_1504	O-acetylhomoserine (Thiol)-lyase.	O-acetylhomoserine (Thiol)-lyase.	0.911
RY70_1555	metE	RY70_1555	RY70_988	O-acetylhomoserine (Thiol)-lyase.	5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.916
RY70_1555	metK	RY70_1555	RY70_718	O-acetylhomoserine (Thiol)-lyase.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.907
RY70_1555	metY	RY70_1555	RY70_1285	O-acetylhomoserine (Thiol)-lyase.	O-acetylhomoserine (Thiol)-lyase.	0.908
adh2	metK	RY70_1710	RY70_718	NAD-dependent aldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.654
cth	RY70_1555	RY70_1504	RY70_1555	O-acetylhomoserine (Thiol)-lyase.	O-acetylhomoserine (Thiol)-lyase.	0.911
cth	metE	RY70_1504	RY70_988	O-acetylhomoserine (Thiol)-lyase.	5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.916
cth	metK	RY70_1504	RY70_718	O-acetylhomoserine (Thiol)-lyase.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.907
cth	metY	RY70_1504	RY70_1285	O-acetylhomoserine (Thiol)-lyase.	O-acetylhomoserine (Thiol)-lyase.	0.911
metE	RY70_1555	RY70_988	RY70_1555	5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	O-acetylhomoserine (Thiol)-lyase.	0.916
metE	cth	RY70_988	RY70_1504	5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	O-acetylhomoserine (Thiol)-lyase.	0.916
metE	metK	RY70_988	RY70_718	5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.977
metE	metY	RY70_988	RY70_1285	5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	O-acetylhomoserine (Thiol)-lyase.	0.916
metK	HgiDIM	RY70_718	RY70_180	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	Cytosine-specific methyltransferase.	0.905
metK	MscL	RY70_718	RY70_70	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	Large-conductance mechanosensitive channel protein.	0.673
metK	PriA	RY70_718	RY70_719	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	Primosomal protein N'.	0.651

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