| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dxs | IspD-2 | RY70_1464 | RY70_810 | 1-deoxy-D-xylulose-5-phosphate synthase. | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 0.710 |
| Dxs | IspE | RY70_1464 | RY70_35 | 1-deoxy-D-xylulose-5-phosphate synthase. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase. | 0.568 |
| Dxs | IspF | RY70_1464 | RY70_847 | 1-deoxy-D-xylulose-5-phosphate synthase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 0.655 |
| Dxs | dxr_1 | RY70_1464 | RY70_590 | 1-deoxy-D-xylulose-5-phosphate synthase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.991 |
| Dxs | ispG_1 | RY70_1464 | RY70_591 | 1-deoxy-D-xylulose-5-phosphate synthase. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.763 |
| Dxs | ispH | RY70_1464 | RY70_678 | 1-deoxy-D-xylulose-5-phosphate synthase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.874 |
| IspD-2 | Dxs | RY70_810 | RY70_1464 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 1-deoxy-D-xylulose-5-phosphate synthase. | 0.710 |
| IspD-2 | IspE | RY70_810 | RY70_35 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase. | 0.898 |
| IspD-2 | IspF | RY70_810 | RY70_847 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 0.988 |
| IspD-2 | RY70_811 | RY70_810 | RY70_811 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | Putative nucleotide sugar dehydratase. | 0.904 |
| IspD-2 | TagG | RY70_810 | RY70_812 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | Teichoic acid translocation permease protein. | 0.567 |
| IspD-2 | TagH | RY70_810 | RY70_813 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | ABC transporter. | 0.521 |
| IspD-2 | dxr_1 | RY70_810 | RY70_590 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.853 |
| IspD-2 | ispG_1 | RY70_810 | RY70_591 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.518 |
| IspD-2 | ispH | RY70_810 | RY70_678 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.782 |
| IspD-2 | uppS | RY70_810 | RY70_594 | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | Isoprenyl transferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.615 |
| IspE | Dxs | RY70_35 | RY70_1464 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase. | 1-deoxy-D-xylulose-5-phosphate synthase. | 0.568 |
| IspE | IspD-2 | RY70_35 | RY70_810 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase. | 2-C-methyl-D-erythritol 4-phosphatecytidylyl transferase. | 0.898 |
| IspE | IspF | RY70_35 | RY70_847 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. | 0.995 |
| IspE | dxr_1 | RY70_35 | RY70_590 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.946 |