node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RY70_1131 | guaA_1 | RY70_1131 | RY70_883 | Inositol-5-monophosphate dehydrogenase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
RY70_1131 | guaB | RY70_1131 | RY70_1529 | Inositol-5-monophosphate dehydrogenase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.963 |
RY70_1131 | hpt | RY70_1131 | RY70_1584 | Inositol-5-monophosphate dehydrogenase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.921 |
RY70_1131 | purL_4 | RY70_1131 | RY70_1436 | Inositol-5-monophosphate dehydrogenase. | Phosphoribosylformylglycinamidine synthase. | 0.861 |
RY70_1131 | pyrG | RY70_1131 | RY70_931 | Inositol-5-monophosphate dehydrogenase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.672 |
RY70_1131 | xpt | RY70_1131 | RY70_909 | Inositol-5-monophosphate dehydrogenase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.919 |
apt | guaA_1 | RY70_1058 | RY70_883 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.982 |
apt | guaB | RY70_1058 | RY70_1529 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.426 |
apt | hpt | RY70_1058 | RY70_1584 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.964 |
apt | purL_4 | RY70_1058 | RY70_1436 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylformylglycinamidine synthase. | 0.673 |
apt | xpt | RY70_1058 | RY70_909 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.900 |
argS | guaA_1 | RY70_304 | RY70_883 | Arginyl-tRNA ligase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.957 |
argS | lysS | RY70_304 | RY70_1635 | Arginyl-tRNA ligase. | Lysine-tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.828 |
argS | purL_4 | RY70_304 | RY70_1436 | Arginyl-tRNA ligase. | Phosphoribosylformylglycinamidine synthase. | 0.543 |
argS | pyrG | RY70_304 | RY70_931 | Arginyl-tRNA ligase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.811 |
guaA_1 | RY70_1131 | RY70_883 | RY70_1131 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inositol-5-monophosphate dehydrogenase. | 0.999 |
guaA_1 | apt | RY70_883 | RY70_1058 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.982 |
guaA_1 | argS | RY70_883 | RY70_304 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Arginyl-tRNA ligase. | 0.957 |
guaA_1 | guaB | RY70_883 | RY70_1529 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA_1 | hpt | RY70_883 | RY70_1584 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |