STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDD15105.1DNA ligase D. (356 aa)    
Predicted Functional Partners:
SDD15033.1
ATP-dependent DNA ligase.
  
 0.998
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.899
SDE62709.1
Bifunctional non-homologous end joining protein LigD.
 
  
0.784
SDD15063.1
Hypothetical protein.
       0.773
SDD15004.1
Hypothetical protein.
       0.594
SDC98184.1
Putative hydrolase.
 
   
 0.537
SDC93317.1
Cell filamentation protein.
      
 0.472
ligA
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
     
 0.472
SDC78415.1
formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.
 
     0.463
Your Current Organism:
Rhodococcus tukisamuensis
NCBI taxonomy Id: 168276
Other names: JCM 11308, NBRC 100609, NCIMB 13903, R. tukisamuensis, Rhodococcus tukisamuensis Matsuyama et al. 2003, strain Mb8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.