STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larCHypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (444 aa)    
Predicted Functional Partners:
SDG12951.1
Uncharacterized protein.
  
 0.991
SDG12991.1
Hypothetical protein.
 
  
 0.978
SDG13053.1
HD domain-containing protein.
       0.773
SDG13093.1
Hypothetical protein.
       0.701
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
      0.688
SDF57339.1
Protein of unknown function.
 
  
 0.513
SDG12740.1
Hypothetical protein.
 
    0.463
SDG39953.1
Uncharacterized conserved protein, DUF362 family.
 
     0.446
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
       0.426
Your Current Organism:
Marvinbryantia formatexigens
NCBI taxonomy Id: 168384
Other names: Bryantella formatexigens, Bryantella formatexigens Wolin et al. 2004, CCUG 46960, DSM 14469, M. formatexigens, Marvinbryantia formatexigens (Wolin et al. 2004) Wolin et al. 2008, strain I-52
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.