STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDG95996.1Ribonucleoside-triphosphate reductase class III activase subunit; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (163 aa)    
Predicted Functional Partners:
nrdD-2
Ribonucleoside-triphosphate reductase class III catalytic subunit.
 
 
 0.962
nrdD
Ribonucleoside-triphosphate reductase class III catalytic subunit.
 
 
 0.961
SDG06719.1
Anaerobic ribonucleoside-triphosphate reductase.
 
 
 0.885
folK
Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
 0.822
SDG95960.1
dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
       0.607
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.597
SDG96034.1
Putative ABC transport system ATP-binding protein.
       0.498
SDG96070.1
Putative ABC transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.
       0.498
folE
GTP cyclohydrolase I.
  
  
 0.482
cbiD
Cobalt-precorrin 5B C1-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.440
Your Current Organism:
Marvinbryantia formatexigens
NCBI taxonomy Id: 168384
Other names: Bryantella formatexigens, Bryantella formatexigens Wolin et al. 2004, CCUG 46960, DSM 14469, M. formatexigens, Marvinbryantia formatexigens (Wolin et al. 2004) Wolin et al. 2008, strain I-52
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