A0A316U2U5 protein (Pseudomicrostroma glucosiphilum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

A0A316U2U5

DUF202 domain-containing protein. (201 aa)

Predicted Functional Partners:

A0A316U3Z2

0.794

A0A316UG24

0.794

A0A316UEW1

0.717

A0A316U2S8

0.579

A0A316U8K7

0.558

A0A316TYG0

0.544

A0A316TZJ8

0.544

A0A316U0B3

0.544

A0A316U134

0.544

A0A316U3J7

0.544

Your Current Organism:

Pseudomicrostroma glucosiphilum

NCBI taxonomy Id: 1684307
Other names: CBS 14053, MCA 4718, Microstromatales sp. MCA4718, NRRL 66310, P. glucosiphilum, Rhodotorula sp. MCA 4718

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A316TYG0	A0A316U2U5	Uncharacterized protein.	DUF202 domain-containing protein.	0.544
A0A316TYG0	A0A316U3Z2	Uncharacterized protein.	Putative Cdk1-cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.635
A0A316TYG0	A0A316UEW1	Uncharacterized protein.	Putative VTC4-vacuolar transporter chaperone.	0.544
A0A316TYG0	A0A316UG24	Uncharacterized protein.	Putative PHO85-cyclin-dependent protein kinase; Belongs to the protein kinase superfamily.	0.635
A0A316TZJ8	A0A316U2U5	TRP-domain-containing protein.	DUF202 domain-containing protein.	0.544
A0A316TZJ8	A0A316U3Z2	TRP-domain-containing protein.	Putative Cdk1-cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.635
A0A316TZJ8	A0A316UEW1	TRP-domain-containing protein.	Putative VTC4-vacuolar transporter chaperone.	0.544
A0A316TZJ8	A0A316UG24	TRP-domain-containing protein.	Putative PHO85-cyclin-dependent protein kinase; Belongs to the protein kinase superfamily.	0.635
A0A316U0B3	A0A316U2U5	Nucleotide-diphospho-sugar transferase.	DUF202 domain-containing protein.	0.544
A0A316U0B3	A0A316U3Z2	Nucleotide-diphospho-sugar transferase.	Putative Cdk1-cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.635
A0A316U0B3	A0A316UEW1	Nucleotide-diphospho-sugar transferase.	Putative VTC4-vacuolar transporter chaperone.	0.544
A0A316U0B3	A0A316UG24	Nucleotide-diphospho-sugar transferase.	Putative PHO85-cyclin-dependent protein kinase; Belongs to the protein kinase superfamily.	0.635
A0A316U134	A0A316U2U5	Uncharacterized protein.	DUF202 domain-containing protein.	0.544
A0A316U134	A0A316U3Z2	Uncharacterized protein.	Putative Cdk1-cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.635
A0A316U134	A0A316UEW1	Uncharacterized protein.	Putative VTC4-vacuolar transporter chaperone.	0.544
A0A316U134	A0A316UG24	Uncharacterized protein.	Putative PHO85-cyclin-dependent protein kinase; Belongs to the protein kinase superfamily.	0.635
A0A316U2S8	A0A316U2U5	PLC-like phosphodiesterase.	DUF202 domain-containing protein.	0.579
A0A316U2S8	A0A316U3Z2	PLC-like phosphodiesterase.	Putative Cdk1-cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.815
A0A316U2S8	A0A316UEW1	PLC-like phosphodiesterase.	Putative VTC4-vacuolar transporter chaperone.	0.579
A0A316U2S8	A0A316UG24	PLC-like phosphodiesterase.	Putative PHO85-cyclin-dependent protein kinase; Belongs to the protein kinase superfamily.	0.815

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

14

average node degree:

2.55

avg. local clustering coefficient:

0.857

expected number of edges:

12

PPI enrichment p-value:

0.331

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0072583

Clathrin-dependent endocytosis

2 of 13

2.68

0.93

0.0414

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0035615

Clathrin adaptor activity

2 of 13

2.68

1.12

0.0214

GO:0003735

Structural constituent of ribosome

3 of 287

1.51

0.78

0.0427

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030122

AP-2 adaptor complex

2 of 6

3.01

1.84

0.0019

GO:0005762

Mitochondrial large ribosomal subunit

3 of 82

2.05

1.68

0.0019

GO:0032991

Protein-containing complex

5 of 3509

0.65

0.39

0.0398

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:11394

Organellar ribosome

3 of 55

2.23

1.75

0.0018

CL:18834

AP-2 adaptor complex, and NECAP, PHear domain

2 of 10

2.79

1.66

0.0033

CL:11397

Organellar large ribosomal subunit, and RRF superfamily

2 of 26

2.38

1.48

0.0054

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-437239

Recycling pathway of L1

2 of 15

2.62

1.29

0.0118

MAP-373760

L1CAM interactions

2 of 25

2.39

1.2

0.0152

MAP-8866427

VLDLR internalisation and degradation

2 of 33

2.27

1.16

0.0171

MAP-9675108

Nervous system development

2 of 52

2.08

1.03

0.0254

MAP-8964038

LDL clearance

2 of 47

2.12

1.03

0.0254

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030122

AP-2 adaptor complex

2 of 4

3.19

1.88

0.0017

GOCC:0005762

Mitochondrial large ribosomal subunit

3 of 74

2.1

1.72

0.0017

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01217

Clathrin adaptor complex small chain

2 of 10

2.79

1.21

0.0158

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR027156

AP-2 complex subunit sigma

2 of 2

3.49

1.64

0.0039

IPR016635

Adaptor protein complex, sigma subunit

2 of 6

3.01

1.38

0.0090

IPR022775

AP complex, mu/sigma subunit

2 of 10

2.79

1.24

0.0142

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