STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A316U5N6Rad52/22 double-strand break repair protein. (143 aa)    
Predicted Functional Partners:
A0A316UET1
Rad51-domain-containing protein.
    
 0.993
A0A316UGS3
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.975
A0A316UBG8
Uncharacterized protein.
    
 0.968
A0A316UHC1
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.967
A0A316U5X7
Uncharacterized protein.
    
 0.940
A0A316U2Q6
ERCC4 domain-containing protein.
   
 0.934
A0A316TZS2
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.922
A0A316TX11
UvrD/REP type DNA helicase.
    
 
 0.917
A0A316U1E1
Ubiquitin-like protein.
    
 0.917
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.917
Your Current Organism:
Pseudomicrostroma glucosiphilum
NCBI taxonomy Id: 1684307
Other names: CBS 14053, MCA 4718, Microstromatales sp. MCA4718, NRRL 66310, P. glucosiphilum, Rhodotorula sp. MCA 4718
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.