A0A316U7G7 protein (Pseudomicrostroma glucosiphilum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

A0A316U7G7

Uncharacterized protein. (144 aa)

Predicted Functional Partners:

A0A316U730

0.711

A0A316U9N1

0.711

A0A316U9V9

0.711

A0A316UAD8

0.711

A0A316UDE0

0.711

A0A316UFD5

0.711

A0A316UFN9

0.711

A0A316UGE0

0.711

A0A316U460

0.704

A0A316UAQ4

0.704

Your Current Organism:

Pseudomicrostroma glucosiphilum

NCBI taxonomy Id: 1684307
Other names: CBS 14053, MCA 4718, Microstromatales sp. MCA4718, NRRL 66310, P. glucosiphilum, Rhodotorula sp. MCA 4718

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A316U460	A0A316U730	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.492
A0A316U460	A0A316U7G7	Uncharacterized protein.	Uncharacterized protein.	0.704
A0A316U460	A0A316U9N1	Uncharacterized protein.	Uncharacterized protein.	0.492
A0A316U460	A0A316U9V9	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.492
A0A316U460	A0A316UAD8	Uncharacterized protein.	Uncharacterized protein.	0.492
A0A316U460	A0A316UDE0	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.492
A0A316U460	A0A316UFD5	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.492
A0A316U460	A0A316UFN9	Uncharacterized protein.	Kinase-like protein.	0.492
A0A316U460	A0A316UGE0	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.492
A0A316U730	A0A316U460	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.492
A0A316U730	A0A316U7G7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.711
A0A316U730	A0A316U9V9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.522
A0A316U730	A0A316UAQ4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.492
A0A316U730	A0A316UDE0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.667
A0A316U730	A0A316UGE0	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.670
A0A316U7G7	A0A316U460	Uncharacterized protein.	Uncharacterized protein.	0.704
A0A316U7G7	A0A316U730	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.711
A0A316U7G7	A0A316U9N1	Uncharacterized protein.	Uncharacterized protein.	0.711
A0A316U7G7	A0A316U9V9	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.711
A0A316U7G7	A0A316UAD8	Uncharacterized protein.	Uncharacterized protein.	0.711

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.843

expected number of edges:

10

PPI enrichment p-value:

0.00224

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008643

Carbohydrate transport

4 of 21

1.46

1.14

0.0022

GO:0055085

Transmembrane transport

10 of 201

0.88

0.89

7.18e-06

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140359

ABC-type transporter activity

5 of 21

1.56

1.61

0.00013

GO:0015423

ABC-type maltose transporter activity

2 of 2

2.18

0.92

0.0197

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055052

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

3 of 3

2.18

1.78

0.00037

GO:0043190

ATP-binding cassette (ABC) transporter complex

4 of 16

1.58

1.48

0.00037

GO:0005886

Plasma membrane

9 of 321

0.63

0.53

0.00037

GO:0016021

Integral component of membrane

9 of 402

0.53

0.43

0.00087

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2210

Mixed, incl. ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing, and ABC-type maltose transporter activity

9 of 11

2.1

5.84

3.86e-15

CL:2208

Mixed, incl. Binding-protein-dependent transport system inner membrane component, and Bacterial extracellular solute-binding protein

11 of 23

1.86

5.35

1.41e-17

CL:2222

Mixed, incl. ABC-type maltose transporter activity, and 5-3 exoribonuclease activity

5 of 5

2.18

3.4

9.67e-08

CL:2212

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing, and ABC-type maltose transporter activity

4 of 5

2.09

2.47

9.30e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sbac02010

ABC transporters

7 of 62

1.24

1.49

3.60e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0055052

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

3 of 3

2.18

1.86

0.00026

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

4 of 21

1.46

1.36

0.00045

GOCC:0005886

Plasma membrane

9 of 217

0.8

0.73

9.91e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0813

Transport

9 of 107

1.11

1.38

2.14e-07

KW-1003

Cell membrane

6 of 122

0.88

0.64

0.0049

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00528

Binding-protein-dependent transport system inner membrane component

6 of 20

1.66

2.37

8.00e-07

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