A0A316UA18 protein (Pseudomicrostroma glucosiphilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A316UA18

Kinase-like protein. (1021 aa)

Predicted Functional Partners:

A0A316UD22

0.734

A0A316U385

0.699

A0A316UBN8

0.699

A0A316UGI3

0.699

A0A316UFD5

0.641

A0A316UD36

0.629

A0A316U9W6

0.622

A0A316U241

0.617

A0A316U308

0.611

A0A316TZY8

0.604

Your Current Organism:

Pseudomicrostroma glucosiphilum

NCBI taxonomy Id: 1684307
Other names: CBS 14053, MCA 4718, Microstromatales sp. MCA4718, NRRL 66310, P. glucosiphilum, Rhodotorula sp. MCA 4718

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A316TZY8	A0A316U241	Ras-domain-containing protein.	Putative CNB1-calcineurin B, regulatory subunit.	0.589
A0A316TZY8	A0A316U308	Ras-domain-containing protein.	Putative FRQ1-regulator of phosphatidylinositol-4-OH kinase.	0.604
A0A316TZY8	A0A316U385	Ras-domain-containing protein.	DUF1348-domain-containing protein.	0.682
A0A316TZY8	A0A316U9W6	Ras-domain-containing protein.	EF-hand.	0.727
A0A316TZY8	A0A316UA18	Ras-domain-containing protein.	Kinase-like protein.	0.604
A0A316TZY8	A0A316UBN8	Ras-domain-containing protein.	Putative myosin regulatory light chain cdc4.	0.682
A0A316TZY8	A0A316UD36	Ras-domain-containing protein.	Putative CDC31-spindle pole body component, centrin.	0.589
A0A316TZY8	A0A316UFD5	Ras-domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.615
A0A316TZY8	A0A316UGI3	Ras-domain-containing protein.	EF-hand; Belongs to the calmodulin family.	0.682
A0A316U241	A0A316TZY8	Putative CNB1-calcineurin B, regulatory subunit.	Ras-domain-containing protein.	0.589
A0A316U241	A0A316U308	Putative CNB1-calcineurin B, regulatory subunit.	Putative FRQ1-regulator of phosphatidylinositol-4-OH kinase.	0.788
A0A316U241	A0A316U385	Putative CNB1-calcineurin B, regulatory subunit.	DUF1348-domain-containing protein.	0.729
A0A316U241	A0A316U9W6	Putative CNB1-calcineurin B, regulatory subunit.	EF-hand.	0.418
A0A316U241	A0A316UA18	Putative CNB1-calcineurin B, regulatory subunit.	Kinase-like protein.	0.617
A0A316U241	A0A316UBN8	Putative CNB1-calcineurin B, regulatory subunit.	Putative myosin regulatory light chain cdc4.	0.714
A0A316U241	A0A316UD36	Putative CNB1-calcineurin B, regulatory subunit.	Putative CDC31-spindle pole body component, centrin.	0.512
A0A316U241	A0A316UGI3	Putative CNB1-calcineurin B, regulatory subunit.	EF-hand; Belongs to the calmodulin family.	0.729
A0A316U308	A0A316TZY8	Putative FRQ1-regulator of phosphatidylinositol-4-OH kinase.	Ras-domain-containing protein.	0.604
A0A316U308	A0A316U241	Putative FRQ1-regulator of phosphatidylinositol-4-OH kinase.	Putative CNB1-calcineurin B, regulatory subunit.	0.788
A0A316U308	A0A316U385	Putative FRQ1-regulator of phosphatidylinositol-4-OH kinase.	DUF1348-domain-containing protein.	0.778

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.695

expected number of edges:

11

PPI enrichment p-value:

9.53e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

9 of 210

1.08

1.29

4.63e-07

GO:0006810

Transport

11 of 304

1.0

1.24

1.05e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140359

ABC-type transporter activity

3 of 23

1.56

0.69

0.0399

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

9 of 333

0.88

0.87

1.21e-05

GO:0016021

Integral component of membrane

7 of 569

0.54

0.34

0.0364

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2973

ABC transporter type 1, transmembrane domain MetI-like, and Bacterial extracellular solute-binding protein

11 of 18

2.23

8.2

3.31e-21

CL:2974

ABC transporter type 1, transmembrane domain MetI-like, and ABC transporter, maltose/maltodextrin import, MalK-like

7 of 12

2.21

5.27

2.19e-12

CL:2997

ABC transporter type 1, transmembrane domain MetI-like, and Bacterial extracellular solute-binding protein

4 of 6

2.27

3.01

1.12e-06

CL:2975

ABC transporter type 1, transmembrane domain MetI-like, and TOBE domain

4 of 6

2.27

3.01

1.12e-06

CL:2986

ABC transporter type 1, transmembrane domain MetI-like, and ABC transporter, maltose/maltodextrin import, MalK-like

3 of 6

2.14

1.97

0.00014

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

11 of 106

1.46

3.01

1.47e-14

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0055052

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

6 of 6

2.45

5.4

1.22e-11

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

9 of 29

1.94

5.0

2.68e-14

GOCC:0110165

Cellular anatomical entity

11 of 1512

0.31

0.27

0.0063

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0813

Transport

9 of 77

1.51

2.81

6.08e-11

KW-1003

Cell membrane

7 of 74

1.42

2.05

1.73e-07

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00528

Binding-protein-dependent transport system inner membrane component

7 of 15

2.11

4.6

4.05e-11

PF13416

Bacterial extracellular solute-binding protein

2 of 3

2.27

0.9

0.0217

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000515

ABC transporter type 1, transmembrane domain MetI-like

7 of 15

2.11

4.45

1.05e-10

IPR035906

MetI-like superfamily

7 of 16

2.09

4.39

1.05e-10

IPR015855

ABC transporter, maltose/maltodextrin import, MalK-like

2 of 2

2.45

0.9

0.0226

IPR008995

Molybdate/tungstate binding, C-terminal

2 of 3

2.27

0.84

0.0282

IPR006059

Bacterial extracellular solute-binding protein

2 of 3

2.27

0.84

0.0282

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About