A0A316UCA5 protein (Pseudomicrostroma glucosiphilum)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

A0A316UCA5

Alpha-glucosidase II; Belongs to the glycosyl hydrolase 31 family. (1062 aa)

Predicted Functional Partners:

A0A316U8X1

0.991

A0A316UDQ4

0.914

A0A316UGF9

0.783

A0A316U3W4

0.723

A0A316UI93

0.686

A0A316U714

0.625

A0A316UBL6

0.615

A0A316U758

0.609

A0A316U8T7

0.580

A0A316UES9

0.575

Your Current Organism:

Pseudomicrostroma glucosiphilum

NCBI taxonomy Id: 1684307
Other names: CBS 14053, MCA 4718, Microstromatales sp. MCA4718, NRRL 66310, P. glucosiphilum, Rhodotorula sp. MCA 4718

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A316U3W4	A0A316U8T7	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.802
A0A316U3W4	A0A316UCA5	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Alpha-glucosidase II; Belongs to the glycosyl hydrolase 31 family.	0.723
A0A316U3W4	A0A316UDQ4	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.947
A0A316U714	A0A316U758	Uncharacterized protein.	Protein disulfide-isomerase.	0.637
A0A316U714	A0A316UBL6	Uncharacterized protein.	Uncharacterized protein.	0.625
A0A316U714	A0A316UCA5	Uncharacterized protein.	Alpha-glucosidase II; Belongs to the glycosyl hydrolase 31 family.	0.625
A0A316U714	A0A316UES9	Uncharacterized protein.	Putative alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	0.567
A0A316U714	A0A316UGF9	Uncharacterized protein.	Calreticulin-domain-containing protein.	0.652
A0A316U714	A0A316UI93	Uncharacterized protein.	Glyco_hydro_63 domain-containing protein.	0.858
A0A316U758	A0A316U714	Protein disulfide-isomerase.	Uncharacterized protein.	0.637
A0A316U758	A0A316U8X1	Protein disulfide-isomerase.	Uncharacterized protein.	0.588
A0A316U758	A0A316UBL6	Protein disulfide-isomerase.	Uncharacterized protein.	0.503
A0A316U758	A0A316UCA5	Protein disulfide-isomerase.	Alpha-glucosidase II; Belongs to the glycosyl hydrolase 31 family.	0.609
A0A316U758	A0A316UGF9	Protein disulfide-isomerase.	Calreticulin-domain-containing protein.	0.941
A0A316U8T7	A0A316U3W4	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.802
A0A316U8T7	A0A316UCA5	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Alpha-glucosidase II; Belongs to the glycosyl hydrolase 31 family.	0.580
A0A316U8T7	A0A316UDQ4	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.714
A0A316U8T7	A0A316UI93	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Glyco_hydro_63 domain-containing protein.	0.433
A0A316U8X1	A0A316U758	Uncharacterized protein.	Protein disulfide-isomerase.	0.588
A0A316U8X1	A0A316UBL6	Uncharacterized protein.	Uncharacterized protein.	0.440

page 1 of 4

Network Stats

number of nodes:

5

number of edges:

10

average node degree:

4

avg. local clustering coefficient:

1

expected number of edges:

4

PPI enrichment p-value:

0.00533

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006418

tRNA aminoacylation for protein translation

5 of 23

1.94

2.9

3.38e-07

GO:0006412

Translation

9 of 114

1.5

2.64

5.14e-10

GO:0044271

Cellular nitrogen compound biosynthetic process

10 of 353

1.05

1.33

1.85e-08

GO:1901566

Organonitrogen compound biosynthetic process

10 of 445

0.95

1.09

1.61e-07

GO:0006520

Cellular amino acid metabolic process

6 of 217

1.04

0.96

0.00031

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140101

Catalytic activity, acting on a tRNA

8 of 41

1.89

4.15

1.49e-11

GO:0004812

aminoacyl-tRNA ligase activity

5 of 24

1.92

2.8

5.53e-07

GO:0050567

glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

3 of 3

2.6

2.67

1.03e-05

GO:0016884

Carbon-nitrogen ligase activity, with glutamine as amido-N-donor

4 of 14

2.06

2.59

4.52e-06

GO:0016874

Ligase activity

9 of 129

1.44

2.49

4.20e-10

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:373

Aminoacyl-tRNA synthetase

4 of 14

2.06

2.09

6.43e-05

CL:389

phenylalanyl-tRNA aminoacylation, and Aminoacyl-tRNA synthetase

3 of 6

2.3

1.84

0.00033

CL:1494

Amine-lyase activity, and glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity

3 of 6

2.3

1.84

0.00033

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

psul00970

Aminoacyl-tRNA biosynthesis

8 of 24

2.12

5.57

5.72e-14

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030956

glutamyl-tRNA(Gln) amidotransferase complex

3 of 3

2.6

2.26

6.46e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0648

Protein biosynthesis

8 of 45

1.85

4.15

4.53e-12

KW-0436

Ligase

9 of 81

1.65

3.44

4.53e-12

KW-0030

Aminoacyl-tRNA synthetase

5 of 20

2.0

3.16

1.09e-07

KW-0067

ATP-binding

9 of 296

1.08

1.35

1.09e-07

KW-0820

tRNA-binding

2 of 11

1.86

0.97

0.0127

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01425

Amidase

2 of 2

2.6

0.92

0.0210

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR045864

Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)

4 of 14

2.06

2.0

0.00010

IPR036928

Amidase signature (AS) superfamily

2 of 2

2.6

0.86

0.0275

IPR023631

Amidase signature domain

2 of 2

2.6

0.86

0.0275

IPR020556

Amidase, conserved site

2 of 2

2.6

0.86

0.0275

IPR000120

Amidase

2 of 2

2.6

0.86

0.0275

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