| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RY69_1099 | pbuX | RY69_1099 | RY69_1101 | Superfamily I DNA and RNA helicase. | Xanthine/uracil permease family protein. | 0.567 |
| RY69_1099 | xpt | RY69_1099 | RY69_1100 | Superfamily I DNA and RNA helicase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.667 |
| RY69_1419 | RY69_984 | RY69_1419 | RY69_984 | Phosphoribosylformylglycinamidine synthase. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.498 |
| RY69_1419 | carA | RY69_1419 | RY69_1368 | Phosphoribosylformylglycinamidine synthase. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.972 |
| RY69_1419 | carB | RY69_1419 | RY69_1367 | Phosphoribosylformylglycinamidine synthase. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.660 |
| RY69_1419 | pbuX | RY69_1419 | RY69_1101 | Phosphoribosylformylglycinamidine synthase. | Xanthine/uracil permease family protein. | 0.529 |
| RY69_1419 | pyrB | RY69_1419 | RY69_986 | Phosphoribosylformylglycinamidine synthase. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.702 |
| RY69_1419 | pyrE | RY69_1419 | RY69_980 | Phosphoribosylformylglycinamidine synthase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.741 |
| RY69_1419 | pyrF | RY69_1419 | RY69_1366 | Phosphoribosylformylglycinamidine synthase. | Orotidine 5'-phosphate decarboxylase. | 0.493 |
| RY69_1419 | pyrF-2 | RY69_1419 | RY69_983 | Phosphoribosylformylglycinamidine synthase. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.493 |
| RY69_1419 | xpt | RY69_1419 | RY69_1100 | Phosphoribosylformylglycinamidine synthase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.665 |
| RY69_984 | RY69_1419 | RY69_984 | RY69_1419 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Phosphoribosylformylglycinamidine synthase. | 0.498 |
| RY69_984 | carA | RY69_984 | RY69_1368 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.985 |
| RY69_984 | carB | RY69_984 | RY69_1367 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.978 |
| RY69_984 | pbuX | RY69_984 | RY69_1101 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Xanthine/uracil permease family protein. | 0.618 |
| RY69_984 | pyrB | RY69_984 | RY69_986 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| RY69_984 | pyrE | RY69_984 | RY69_980 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.982 |
| RY69_984 | pyrF | RY69_984 | RY69_1366 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotidine 5'-phosphate decarboxylase. | 0.828 |
| RY69_984 | pyrF-2 | RY69_984 | RY69_983 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.964 |
| carA | RY69_1419 | RY69_1368 | RY69_1419 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase. | 0.972 |