| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RY69_1106 | RY69_1294 | RY69_1106 | RY69_1294 | Pyrazinamidase/Nicotinamidase. | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | 0.525 |
| RY69_1106 | gyrB | RY69_1106 | RY69_2054 | Pyrazinamidase/Nicotinamidase. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.513 |
| RY69_1106 | rpsL | RY69_1106 | RY69_1411 | Pyrazinamidase/Nicotinamidase. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.561 |
| RY69_1294 | RY69_1106 | RY69_1294 | RY69_1106 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Pyrazinamidase/Nicotinamidase. | 0.525 |
| RY69_1294 | RY69_1295 | RY69_1294 | RY69_1295 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Hypothetical protein. | 0.773 |
| RY69_1294 | RY69_1296 | RY69_1294 | RY69_1296 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Haloacid dehalogenase-like hydrolase (HAD superfamily). | 0.829 |
| RY69_1294 | RY69_1297 | RY69_1294 | RY69_1297 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Hypothetical protein. | 0.833 |
| RY69_1294 | RY69_1299 | RY69_1294 | RY69_1299 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Transporter. | 0.515 |
| RY69_1294 | RY69_1300 | RY69_1294 | RY69_1300 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Putative HD domain protein. | 0.517 |
| RY69_1294 | gyrB | RY69_1294 | RY69_2054 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.514 |
| RY69_1294 | nadK | RY69_1294 | RY69_1290 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.630 |
| RY69_1294 | rpsL | RY69_1294 | RY69_1411 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.512 |
| RY69_1294 | tyrS | RY69_1294 | RY69_1298 | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | Tyrosine-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.774 |
| RY69_1295 | RY69_1294 | RY69_1295 | RY69_1294 | Hypothetical protein. | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | 0.773 |
| RY69_1295 | RY69_1296 | RY69_1295 | RY69_1296 | Hypothetical protein. | Haloacid dehalogenase-like hydrolase (HAD superfamily). | 0.773 |
| RY69_1295 | RY69_1297 | RY69_1295 | RY69_1297 | Hypothetical protein. | Hypothetical protein. | 0.773 |
| RY69_1295 | RY69_1299 | RY69_1295 | RY69_1299 | Hypothetical protein. | Transporter. | 0.451 |
| RY69_1295 | RY69_1300 | RY69_1295 | RY69_1300 | Hypothetical protein. | Putative HD domain protein. | 0.451 |
| RY69_1295 | tyrS | RY69_1295 | RY69_1298 | Hypothetical protein. | Tyrosine-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.689 |
| RY69_1296 | RY69_1294 | RY69_1296 | RY69_1294 | Haloacid dehalogenase-like hydrolase (HAD superfamily). | Hemolysin-like protein with S4 and FtsJ-like methyltransferase domains. | 0.829 |
