STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (385 aa)    
Predicted Functional Partners:
RY69_12
Homoserine dehydrogenase.
 
 0.999
thrC
Threonine synthase.
 
 0.998
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.861
RY69_1487
Cysteine synthase A.
     
 0.839
RY69_1266
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.833
ilvE
Branched-chain-amino-acid transaminase.
  
 
 0.828
RY69_1360
Cystathionine beta-lyase.
  
 
 0.822
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
    
 0.822
RY69_1486
Cystathionine gamma-synthase.
  
 
 0.822
RY69_1170
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase.
    
  0.810
Your Current Organism:
Bifidobacterium breve
NCBI taxonomy Id: 1685
Other names: AS 1.2213, ATCC 15700, B. breve, BCRC 11846, Bifidobacterium parvulorum, CCRC 11846, CCRC:11846, CCUG 18365, CCUG 30511 A, CIP 64.69, DSM 20213, HAMBI 558, LMG 11042, LMG:11042, NCAIM B.01820, NCFB 2257, NCIMB 702257, NCTC 11815
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