gmk protein (Bifidobacterium breve) - STRING interaction network

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Score

gmk

Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (196 aa)

Predicted Functional Partners:

guaA

0.989

rpoZ

0.973

hpt

0.958

apt

0.957

pyrF

0.946

xpt

0.940

pyk

0.926

RY69_646

0.919

RY69_1645

0.912

RY69_2082

0.909

Your Current Organism:

Bifidobacterium breve

NCBI taxonomy Id: 1685
Other names: AS 1.2213, ATCC 15700, B. breve, BCRC 11846, Bifidobacterium parvulorum, CCRC 11846, CCRC:11846, CCUG 18365, CCUG 30511 A, CIP 64.69, DSM 20213, HAMBI 558, LMG 11042, LMG:11042, NCAIM B.01820, NCFB 2257, NCIMB 702257, NCTC 11815

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RY69_1645	apt	RY69_1645	RY69_877	Glutamine amidotransferase Class I.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.921
RY69_1645	gmk	RY69_1645	RY69_1365	Glutamine amidotransferase Class I.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.912
RY69_1645	guaA	RY69_1645	RY69_1207	Glutamine amidotransferase Class I.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.918
RY69_1645	hpt	RY69_1645	RY69_316	Glutamine amidotransferase Class I.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.913
RY69_1645	xpt	RY69_1645	RY69_1100	Glutamine amidotransferase Class I.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.921
RY69_2082	RY69_646	RY69_2082	RY69_646	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.902
RY69_2082	gmk	RY69_2082	RY69_1365	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.909
RY69_2082	guaA	RY69_2082	RY69_1207	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.490
RY69_2082	pyk	RY69_2082	RY69_1237	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.905
RY69_646	RY69_2082	RY69_646	RY69_2082	GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.902
RY69_646	gmk	RY69_646	RY69_1365	GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.919
RY69_646	pyk	RY69_646	RY69_1237	GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.907
apt	RY69_1645	RY69_877	RY69_1645	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Glutamine amidotransferase Class I.	0.921
apt	gmk	RY69_877	RY69_1365	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.957
apt	guaA	RY69_877	RY69_1207	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.983
apt	hpt	RY69_877	RY69_316	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.964
apt	xpt	RY69_877	RY69_1100	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.900
gmk	RY69_1645	RY69_1365	RY69_1645	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Glutamine amidotransferase Class I.	0.912
gmk	RY69_2082	RY69_1365	RY69_2082	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.909
gmk	RY69_646	RY69_1365	RY69_646	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.919

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