| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RY69_1028 | RY69_984 | RY69_1028 | RY69_984 | Glutamate synthase [NADPH] large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.425 |
| RY69_1028 | argF | RY69_1028 | RY69_1308 | Glutamate synthase [NADPH] large chain. | Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.690 |
| RY69_1028 | argG | RY69_1028 | RY69_1306 | Glutamate synthase [NADPH] large chain. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.655 |
| RY69_1028 | carA | RY69_1028 | RY69_1368 | Glutamate synthase [NADPH] large chain. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.936 |
| RY69_1028 | carB | RY69_1028 | RY69_1367 | Glutamate synthase [NADPH] large chain. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.972 |
| RY69_1028 | purF | RY69_1028 | RY69_1432 | Glutamate synthase [NADPH] large chain. | Amidophosphoribosyltransferase. | 0.939 |
| RY69_984 | RY69_1028 | RY69_984 | RY69_1028 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Glutamate synthase [NADPH] large chain. | 0.425 |
| RY69_984 | carA | RY69_984 | RY69_1368 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.971 |
| RY69_984 | carB | RY69_984 | RY69_1367 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.953 |
| RY69_984 | pyrB | RY69_984 | RY69_986 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| RY69_984 | pyrE | RY69_984 | RY69_980 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.971 |
| RY69_984 | pyrF | RY69_984 | RY69_1366 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotidine 5'-phosphate decarboxylase. | 0.800 |
| RY69_984 | pyrI | RY69_984 | RY69_985 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase regulatory chain. | 0.983 |
| argF | RY69_1028 | RY69_1308 | RY69_1028 | Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Glutamate synthase [NADPH] large chain. | 0.690 |
| argF | argG | RY69_1308 | RY69_1306 | Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.998 |
| argF | carA | RY69_1308 | RY69_1368 | Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.945 |
| argF | carB | RY69_1308 | RY69_1367 | Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.984 |
| argF | pyrB | RY69_1308 | RY69_986 | Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.866 |
| argF | pyrI | RY69_1308 | RY69_985 | Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Aspartate carbamoyltransferase regulatory chain. | 0.833 |
| argG | RY69_1028 | RY69_1306 | RY69_1028 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Glutamate synthase [NADPH] large chain. | 0.655 |