| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RY69_1419 | RY69_430 | RY69_1419 | RY69_430 | Phosphoribosylformylglycinamidine synthase. | Adenylosuccinate lyase. | 0.995 |
| RY69_1419 | purA | RY69_1419 | RY69_1947 | Phosphoribosylformylglycinamidine synthase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.967 |
| RY69_1419 | purC | RY69_1419 | RY69_1418 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.998 |
| RY69_1419 | purD | RY69_1419 | RY69_1435 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.999 |
| RY69_1419 | purE | RY69_1419 | RY69_1452 | Phosphoribosylformylglycinamidine synthase. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
| RY69_1419 | purF | RY69_1419 | RY69_1432 | Phosphoribosylformylglycinamidine synthase. | Amidophosphoribosyltransferase. | 0.997 |
| RY69_1419 | purH | RY69_1419 | RY69_873 | Phosphoribosylformylglycinamidine synthase. | Bifunctional purine biosynthesis protein PurH. | 0.996 |
| RY69_1419 | purK | RY69_1419 | RY69_1451 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.996 |
| RY69_1419 | purM | RY69_1419 | RY69_1434 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.999 |
| RY69_1419 | purT | RY69_1419 | RY69_1417 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.999 |
| RY69_430 | RY69_1419 | RY69_430 | RY69_1419 | Adenylosuccinate lyase. | Phosphoribosylformylglycinamidine synthase. | 0.995 |
| RY69_430 | purA | RY69_430 | RY69_1947 | Adenylosuccinate lyase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.995 |
| RY69_430 | purC | RY69_430 | RY69_1418 | Adenylosuccinate lyase. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.998 |
| RY69_430 | purD | RY69_430 | RY69_1435 | Adenylosuccinate lyase. | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.974 |
| RY69_430 | purE | RY69_430 | RY69_1452 | Adenylosuccinate lyase. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.990 |
| RY69_430 | purF | RY69_430 | RY69_1432 | Adenylosuccinate lyase. | Amidophosphoribosyltransferase. | 0.990 |
| RY69_430 | purH | RY69_430 | RY69_873 | Adenylosuccinate lyase. | Bifunctional purine biosynthesis protein PurH. | 0.994 |
| RY69_430 | purK | RY69_430 | RY69_1451 | Adenylosuccinate lyase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.992 |
| RY69_430 | purM | RY69_430 | RY69_1434 | Adenylosuccinate lyase. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.989 |
| RY69_430 | purT | RY69_430 | RY69_1417 | Adenylosuccinate lyase. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.887 |
