Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (440 aa)    
Predicted Functional Partners:
RY69_1106
Pyrazinamidase/Nicotinamidase.
 
 0.992
nadC
Nicotinate-nucleotide diphosphorylase (Carboxylating); Belongs to the NadC/ModD family.
   
 0.974
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.951
RY69_620
Competence/damage-inducible protein CinA; Belongs to the CinA family.
  
 
 0.927
RY69_1549
Phosphohydrolase (MutT/nudix family protein).
    
 0.906
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.784
RY69_117
Bacterial capsule synthesis protein.
  
    0.702
RY69_1631
Hypothetical protein.
       0.675
pepN
Aminopeptidase.
 
 
 
 0.419
nadA
Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
  
 0.414
Your Current Organism:
Bifidobacterium breve
NCBI taxonomy Id: 1685
Other names: AS 1.2213, ATCC 15700, B. breve, BCRC 11846, Bifidobacterium parvulorum, CCRC 11846, CCRC:11846, CCUG 18365, CCUG 30511 A, CIP 64.69, DSM 20213, HAMBI 558, LMG 11042, LMG:11042, NCAIM B.01820, NCFB 2257, NCIMB 702257, NCTC 11815
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