Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RY69_2070MutT/NUDIX family protein; Belongs to the Nudix hydrolase family. (328 aa)    
Predicted Functional Partners:
RY69_2071
tRNA adenylyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.683
crgA
Membrane protein; Involved in cell division; Belongs to the CrgA family.
  
     0.573
ileS
Isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
    0.501
RY69_2234
Hydrolase, NUDIX family.
  
     0.487
RY69_1901
Flp pilus assembly protein.
  
     0.483
RY69_91
DNA and RNA helicase-like protein.
 
     0.465
leuS
Leucine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.428
RY69_1347
Phosphotransferase enzyme domain protein.
 
     0.410
pyrF
Orotidine 5'-phosphate decarboxylase.
 
     0.404
RY69_1543
Transcriptional regulator, Crp/Fnr family.
 
  
 0.402
Your Current Organism:
Bifidobacterium breve
NCBI taxonomy Id: 1685
Other names: AS 1.2213, ATCC 15700, B. breve, BCRC 11846, Bifidobacterium parvulorum, CCRC 11846, CCRC:11846, CCUG 18365, CCUG 30511 A, CIP 64.69, DSM 20213, HAMBI 558, LMG 11042, LMG:11042, NCAIM B.01820, NCFB 2257, NCIMB 702257, NCTC 11815
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