| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCOR_0158 | BCOR_0159 | BCOR_0158 | BCOR_0159 | Molecular chaperone DnaJ. | Heat shock regulatory protein hspR. | 0.938 |
| BCOR_0158 | dnaK | BCOR_0158 | BCOR_0156 | Molecular chaperone DnaJ. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.998 |
| BCOR_0158 | groL | BCOR_0158 | BCOR_0926 | Molecular chaperone DnaJ. | GroEL 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.773 |
| BCOR_0158 | grpE | BCOR_0158 | BCOR_0157 | Molecular chaperone DnaJ. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.965 |
| BCOR_0158 | hrcA | BCOR_0158 | BCOR_0692 | Molecular chaperone DnaJ. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.675 |
| BCOR_0158 | sigA | BCOR_0158 | BCOR_0546 | Molecular chaperone DnaJ. | RNA polymerase principal sigma factor HrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.501 |
| BCOR_0159 | BCOR_0158 | BCOR_0159 | BCOR_0158 | Heat shock regulatory protein hspR. | Molecular chaperone DnaJ. | 0.938 |
| BCOR_0159 | BCOR_0442 | BCOR_0159 | BCOR_0442 | Heat shock regulatory protein hspR. | Glutamine synthetase GlnA. | 0.571 |
| BCOR_0159 | dnaJ | BCOR_0159 | BCOR_0691 | Heat shock regulatory protein hspR. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.824 |
| BCOR_0159 | dnaK | BCOR_0159 | BCOR_0156 | Heat shock regulatory protein hspR. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.909 |
| BCOR_0159 | groL | BCOR_0159 | BCOR_0926 | Heat shock regulatory protein hspR. | GroEL 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.670 |
| BCOR_0159 | grpE | BCOR_0159 | BCOR_0157 | Heat shock regulatory protein hspR. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.949 |
| BCOR_0159 | hrcA | BCOR_0159 | BCOR_0692 | Heat shock regulatory protein hspR. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.702 |
| BCOR_0159 | rpoB | BCOR_0159 | BCOR_0346 | Heat shock regulatory protein hspR. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.579 |
| BCOR_0159 | rpoZ | BCOR_0159 | BCOR_0950 | Heat shock regulatory protein hspR. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.604 |
| BCOR_0159 | sigA | BCOR_0159 | BCOR_0546 | Heat shock regulatory protein hspR. | RNA polymerase principal sigma factor HrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.674 |
| BCOR_0442 | BCOR_0159 | BCOR_0442 | BCOR_0159 | Glutamine synthetase GlnA. | Heat shock regulatory protein hspR. | 0.571 |
| dnaJ | BCOR_0159 | BCOR_0691 | BCOR_0159 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat shock regulatory protein hspR. | 0.824 |
| dnaJ | dnaK | BCOR_0691 | BCOR_0156 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
| dnaJ | groL | BCOR_0691 | BCOR_0926 | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | GroEL 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.872 |
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